European active surveillance study of women taking HRT (EURAS-HRT): study protocol [NCT00214903]

European active surveillance study of women taking HRT (EURAS-HRT): study protocol [NCT00214903]

BACKGROUND The post marketing safety surveillance program for a drug containing a new chemical entity should assess both, the safety outcomes that relate specifically to the targeted population, as well as those that could potentially be related to special pharmacological characteristics of the drug. Active safety surveillance using valid epidemiological study designs has been proven to be a pe...

Hormone replacement therapy (HRT).

Journal of Family Planning and Reproductive Health Care 2004: 30(1) Introduction “I’m confused, anxious, wary. The press coverage on hormone replacement therapy (HRT) has left me feeling concerned and, frankly, troubled. Is HRT a good thing or isn’t it? Should I be taking it or shouldn’t I? I’ve even become doubtful about taking medical advice on all this. To be frank, I’m going to gather infor...

International Active Surveillance Study of Women Taking Oral Contraceptives (INAS-OC Study)

BACKGROUND A 24-day regimen of contraceptive doses of drospirenone and ethinylestradiol (DRSP/EE 24d) was recently launched. This regimen has properties which may be beneficial for certain user populations (e.g., women suffering from premenstrual dysphoric disorder or acne). However, it is unknown whether this extended regimen has an impact on the cardiovascular risk associated with the use of ...

HRT and heart disease.

BioTE HRT/BHRT MetaAnalysis

There have been many articles published regarding the benefits of HRT and BHRT; particularly in breast cancer, prostate cancer, cardiovascular protection, and bone building/osteoarthritis. The purpose of this white paper is to summarize the results of these articles by each disease entity. Please note, however, that most of the articles did not specify HRT or BHRT, but the hormone therapy itsel...